根据Richard Matheson的同名小说改编。Robert Neville是生化武器荼毒世界之后的“生还者”之一。虽然在生化战争后的世界上存活了几百个“人”，可是他们已经变异，害怕阳光，嗜杀人，他们组成一个族群。Neville必须使用各种手段消灭他们。
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