“因子8号”又称抗血友病球蛋白，作为凝血过程中的辅助因子参与凝血。本片便是围绕着这一特殊的凝血剂展开，讲述了一群从泰国返回德国的游客因感染了变异流感而被滞留在飞机上等待检测治疗，最终乘客们为了生存飞往无人岛的故事。
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