《150小时》讲述几位爱好长跑的高校教师利用公益挑战活动为云南贫困学校女教师筹建厕所的故事。7名业余跑者需要在150小时内穿越400公里青海无人区，只有当一人在规定时间内跑完全程，方可筹得善款。到底他们为何选择并信奉需要时刻面对诸多恶略自然环境以及巨大不确定性这样的挑战方式，而这样的挑战最终能为众人带来什么，也许只有在行进的路途中才能一一知晓。
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